Laboratory Equipment

Homogenizers play a crucial role in labs. Homogenization is an important process used to prepare samples for the analysis of proteins and acids, pathogens, metabolism, the study of cells, and various types of material. There are many different models of homogenizers that use a variety of techniques on the market today. Each model and method has its own distinct advantages and disadvantages.

What is a Laboratory Homogenizer?

A lab homogenizer is a piece of lab equipment that mixes a solution in order to create a consistent and uniform mixture. It breaks the components down and distributes them evenly throughout the solution. These components either don’t mix together or are immiscible, are made up of different sizes, or are in a variety of phases.

What is the Purpose of a Homogenizer?

The main purpose of a homogenizer is to create a mixture where the composition is uniform throughout. The mixture is blended so thoroughly that individual substances can not be detected. Homogenizers also serve as a device for dissolving, emulsifying, dispersing, grinding, and suspending.

What is an Ultrasonic Homogenizer?

One type of homogenizer is the ultrasonic homogenizer. These devices homogenize samples using ultrasonic waves by breaking up cell structures in suspension and creating emulsions. These devices consist of a power generator, a control, a converter that changes electrical energy into mechanical motion, and a probe that transmits energy to the sample.

Ultrasonic homogenizers can be used for several applications. They can be used to create emulsions, break up suspended particles, disperse nanoparticles, break apart cell structures in suspension, and shear DNA.

How Do Ultrasonic Homogenizers Work?

Ultrasonic homogenizers have their own special technique for homogenizing samples. In this technique, sound waves cause bubbles that are used to disrupt cells and tissue. The quick vibration of the probe or tip creates bubbles that form and dissipate. This action breaks up any particles or cells in the solution. Ultrasonic homogenizers must have enough power or wattage to tackle larger or more challenging samples or to process samples quickly.

What are the Disadvantages to Using the Ultrasonication Technique?

There are times when the ultrasonication technique is not as effective as other models. One of these times is when tissue samples are intact. The ultrasonic technique works better when the sample is processed as a suspension. Also, ultrasonic homogenizers are not always compatible with temperature-sensitive samples due to the fact that the device generates a fair amount of heat itself. The high power of the sound waves also create a hazard and it is recommended that you wear ear protection.

What are Some Homogenizer Accessories?

There are accessories for homogenizers that make them more practical for certain applications. Some of these accessories include stands and clamps for stability, cup horns to control cross-contamination, and overhead stirrers. The overhead stirrers vary based on speed, flow, and viscosity desired. There are also various tips to reduce sample retention, mixing rotors, generators, and probes.

Where Can I Purchase a Laboratory Homogenizer and How Much Does it Cost?

Lab Pro offers a large variety of chemicals and laboratory supplies. For over 40 years, Lab Pro Inc. has been committed to delivering the highest quality homogenizers, microscopes, chemicals, tweezers, hard-wire cutters, lab supplies, and cleanroom PPE apparel to medical device and electronic manufacturing companies and laboratories worldwide. To learn more, visit the biggest Lab Supply showroom in California, or contact us online at 888-452-2776.